#04025: DNA and Protein Library Construction Methodology

 A method for building and polymerizing artificial coding sequence (6-mers) for the creation of unique nucleic acids and proteins from a limited number of amino acids 
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TECH FIELD(S)
Research Tool
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FEATURES
A method for producing novel libraries with limited amino acid diversity that contain structurally and biologically relevant nucleic acids and proteins.  The method polymerizes six nucleotide (6-mer) codons; these duplexes are themselves multi-merized together.  The resulting nucleic acids and proteins are of varying length and form secondary, tertiary and quaternary structures based upon intentional amino acid design. 
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BENEFITS

  • Product length as variable in library
  • Not restrained to degenerate regions of the code
  • These libraries necessarily exclude amino acids that serve to interrupt secondary structure

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INVENTOR(S)
Jim Drummond, Dan Maillet – Department of Biology
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INTELLECTUAL PROPERTY STATUS
PCT application available for licensing
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CONTACT INFORMATION
For additional information on this technology, please contact Doug Bodde, Business Development Manager, IURTC:

Indiana University Research & Technology Corporation
351 West 10th Street
Indianapolis, IN 46202
Telephone: 812.855.1608
dbodde@iu.edu
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